Allergy Profile / Peanut Test

Allergy Profile / Peanut Test

Allergy Testing

The Allergy Profile / Peanut Test measures the presence of IgE antibodies to specific peanut proteins, aiding in the diagnosis of peanut allergies and assessing the risk of severe allergic reactions. With approximately 2.5% of North American school-aged children affected by peanut allergies, this test differentiates between true allergies and milder sensitizations, enabling more accurate management and prevention strategies.

$137.00
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  • Purpose of the Test:
  • This test is designed to measure IgE antibodies to specific peanut proteins, providing valuable information on the type and strength of allergic responses to peanuts.
  • Prevalence:
  • Peanut allergies affect about 2.5% of school-aged children and approximately 1.2% of the total U.S. population, with rapid onset of severe symptoms, such as anaphylaxis, in cases of true peanut allergies.
  • Clinical Background:
  • Diagnosis is typically based on clinical history and sensitization testing, which includes IgE antibody response to whole-food peanut extract or skin-prick testing.
  • Testing Methodology:
  • IgE sensitivity can be assessed through whole-food testing or peanut component testing:
  • Whole-Food Testing: May not clearly distinguish between true allergies and mild sensitizations, as it can include individuals sensitized to birch tree pollen or other mild allergens.
  • Peanut Component Testing: Identifies specific allergens associated with either mild or true peanut allergies, improving diagnostic accuracy.
  • Key Peanut Allergens Tested:
  • The Peanut Component Panel assesses IgE antibodies to the following allergens:
  • Ara h 1, Ara h 2, Ara h 3: Main allergens associated with severe reactions (97% of individuals with true peanut allergies are sensitized to at least one of these).
  • Ara h 6: Considered for individuals with suspected peanut allergy, particularly if they are not sensitized to Ara h 1-3 or Ara h 9.
  • Ara h 9: Lipid-transfer protein associated with severe reactions, mainly in Mediterranean regions but also present in the U.S. population.
  • Ara h 8: Linked to mild reactions like oral allergy syndrome (OAS); individuals sensitized to Ara h 8 are generally peanut tolerant.
  • Risk Assessment:
  • Identifying sensitization to specific peanut component allergens assists healthcare providers in evaluating a patient’s risk for severe systemic reactions, enabling tailored management plans.

This test is an essential tool for individuals with suspected peanut allergies, facilitating accurate diagnosis and effective allergy management.

Why would I need a Allergy Profile / Peanut Test ?
The Allergy Profile / Peanut Test may be recommended if: You have experienced allergic reactions after consuming peanuts, such as hives, swelling, difficulty breathing, abdominal pain, or anaphylaxis. You have a history of atopic dermatitis, asthma, or eczema, which may increase your risk for peanut allergies. Previous tests, such as a standard peanut IgE test or skin prick test, showed positive results, but the severity and specific components involved are unclear. You need to differentiate between a true peanut allergy and a cross-reactive allergy, such as one involving birch pollen, which can sometimes mimic peanut allergy symptoms but is generally less severe. You are undergoing a desensitization or treatment program for peanut allergy, and your healthcare provider wants to monitor specific peanut component IgE levels.
What happens if my test results indicate a peanut allergy?
If the test results show elevated levels of IgE antibodies to specific peanut components: Dietary modifications: Avoid peanuts entirely, especially if you are sensitive to proteins like Ara h 2, which are associated with severe reactions. Emergency action plan: If you are at risk for anaphylaxis, you may be advised to carry an epinephrine auto-injector (EpiPen). Your provider will provide guidance on how and when to use it. Further testing: Additional tests, such as an oral food challenge under medical supervision, may be performed to confirm the allergy and evaluate its severity. Consultation with an allergist: You may be referred to an allergist for specialized care and ongoing monitoring of your peanut allergy.